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Observe Intently (1)pentobarbital will reduce the extent or effect of mifepristone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. CYP3A4 inducers have not been researched, coadministration not advised by producerReserve concomitant prescribing of such drugs in sufferers for whom other cure selections are inade